RAB10 variants implicated in AD resilience
We identified naturally occurring genetic variants in the RAB10 gene that protect against Alzheimer's disease.
Research Record
We have a strong track record of publishing high-quality manuscripts that directly impact the broad scientific community.
126
Number of Publications
$6.6 million
External Grant Money
41
Number of Collaborative Projects
A selection of publications from the lab are shown below:
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Lingering Taxonomic Challenges Hinder Conservation and Management of Global Bonefishes
A comprehensive review of bonefish.
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Atypical chemokine receptor ACKR2-V41A has decreased CCL2 binding, scavenging, and activation, supporting sustained inflammation and increased Alzheimer’s disease risk
Understanding protein binding affinity could lead to a potential Alzheimer's disease drug target at the ACKR2-V41A chemokine receptor.
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Assessment of the genetic variance of late-onset Alzheimer’s disease
We determined the extent to which genetics impact Alzheimer's disease onset.
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Population genealogy resource shows evidence of familial clustering for Alzheimer's disease
We identified families with more cases of Alzheimer's disease than the general population using genealogical records
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Common DNA Variants Accurately Rank an Individual of Extreme Height
We found out that Shawn Bradley is extremely tall because he has a lot of common genetic variants that contribute to his height.
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Population-based analysis of Alzheimer’s disease risk alleles implicates genetic interactions
In order to fully understand the genetic basis of Alzheimer’s disease risk we must improve our efforts to characterize gene-gene and gene-environment interactions
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